退化性關節炎目前成因不明。先前大多數人認為疾病是因為過度使用使得關節軟骨磨損加速的關係,但這一點並沒有在所有的病人身上發生。有些人一輩子務農或做粗重工作,但關節卻很健康。有些人的工作是坐辦公室,還沒退休卻已經有關節退化的現象。我們雖然不知道確切的成因,但是有一些是我們已經知道的危險因子:
這些危險因子中,僅有體重是我們自己可以控制的。適度控制體重是保護關節、避免關節退化的最好方式。另外,運動傷害、意外傷害發生後,也需要做適當的處理,避免關節退化的後遺症產生。
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